Diabetes is a metabolic disease that develops when the secretory gland called the pancreas does not produce enough insulin hormone in your body or the insulin hormone it produces cannot be used effectively.
Our digestive system breaks down the eating into nutrients. Carbohydrates or various sugars are broken down into glucose for use by the body and absorbed. Glucose is an important fuel source for many organs in our body. However, in order to use glucose as a fuel, the glucose molecule must enter the cell. For this reason, we need a special hormone. Beta cells in the pancreas produce a hormone called insulin.
Insulin is the chemical messenger necessary for the entry of glucose into the cell to regulate blood sugar levels that rise after a meal. Insulin is released into the bloodstream to trigger blood glucose to enter cells. Insulin lowers your blood sugar level, allowing glucose to enter the cell.
Not only insulin but also glucagon which has an effect on blood sugar levels. If your blood sugar levels are too low or you haven’t eaten for too long, glucagon inform the liver to release stored sugar.
The other active hormone in diabetes is GLP-1 which helps the pancreas for production of the right amount of insulin to move sugar from the blood into the cells. When blood sugar gets too high, GLP-1 stimulates beta cells to increase insulin production and also helps lower the amount of sugar converted by the liver. When blood sugar gets too high, insulin production increases. Metabolic disorders in these systems lead to diabetes.
These days, autumn makes itself felt, unpredictable weather causes an increase in flu cases. It is possible to protect against influenza, which can be seen more frequently in crowded environments, by vaccination.
Influenza is an infectious disease which is disease that enters the body through the respiratory tract with viruses called “influenza”. Influenza can cause epidemics, especially in late autumn, winter, and early spring.
Healthy individuals injected with flu viruses usually heal spontaneously in one week. However, it can cause serious and fatal complications especially in the elderly, children, and people with chronic diseases
Influenza, which is a contagious virus infection, is a much more severe disease than the common cold. The flu virus, which can survive for weeks, especially in the winter, is very easy to transmit. One of the most important ways to protect against the flu is the flu vaccine.
The flu vaccine is inactive and is prepared each year according to the World Health Organization’s recommendations. After the flu vaccine is administered, the protective antibody level is formed on average, 10-15 days. It can prevent 70-90% of flu symptoms in healthy young adults.
Who can have the flu vaccine?
Flu vaccines are suitable for most people with rare exceptions
- people 50 years and older
- People with chronic diseases in a nursing home
- People with chronic diseases such as chronic obstructive pulmonary disease (asthma, chronic bronchitis, etc.), heart patients, diabetics, chronic liver and kidney patients,
- Those with immunologic diseases.
- Those with immune-suppressed diseases suppressed immune system (HIV/AIDS patients, cancer patients, organ and bone marrow transplant recipients, chemotherapy, radiotherapy patients, steroids)
- Between 6 months and 18 months and taking long-term aspirin therapy (to reduce the risk of developing Reye’s syndrome),
- Pregnant women (within the knowledge of the patient’s physician),
- Babies older than six months (trivalent inactivated flu vaccine), older than thirty-six months (3 years old) (trivalent or quadrivalent flu vaccine can be administered),
- Health workers,
- All healthy individuals who want to be protected by vaccination can get vaccinated.
Unfortunately, Coronavirus does not affect only adults, children can also develop COVID-19.
Most of the cases are not showing the symptoms and Covid-19 in children usually have milder symptoms when compared to adults. However, some children might develop severe complications and need to hospitalize.
The symptoms of Covid in children are similar and we list few main Covid-19 symptoms;
If you are suspicious that your kid might have a Covid-19 infection, you should get a PCR test and isolate the kid from family members and visitors. And of course, the kid should stay home until receiving the result of the PCR test. If the symptoms get any worse, you should call your doctor or admit to the closest ER.
Getting Covid-19 again seems to be rare but you have a still possible to get Covid-19 again after the recovery of it.
It is called reinfection. According to the knowledge from similar viruses, reinfections are expected.
This situation is also valid for vaccinated people. If you got the shot of Covid Vaccine and still virus can infect you again and thanks to the vaccine, the risk of severe illness and death decrease significantly.
There is a study called SARS-CoV-2 Immunity and Reinfection Evaluation (SIREN) which was conducted by the Department of Health and Social Care and Public Health in England. The study showed that the possibility of reinfection is decreased by 83% for at least five months due to the responses of the immune from the previous infection.
The results from the same study suggested that cases of reinfection are rare and the ratio of occurrence is fewer than 1% of about 6.600 participants who had already been infected by the COVID-19 virus.
Reinfection is a rare situation but it is significant to take precautions such as wearing masks, handwashing, and social distancing.
Created in 1997 by Inserm, Orphanet has progressively transformed into a Consortium of 40 countries, which are principally located in Europe. These partners work together to pool within it the available data on rare diseases taken from the scientific literature, making Orphanet the most comprehensive resource in the field. The large amounts of information it contains can improve the understanding of these conditions.
In their study, Rath’s team examined the data available on the point prevalence of 3,585 rare diseases (namely, the number of people affected at a given time). Rare cancers as well as rare diseases caused by infection or poisoning were excluded from their analysis.
After harmonizing the literature data using a predefined method, following which they added together the point prevalence of the various diseases referenced in the database, they were able to estimate that at any given time, 3.5 to 5.9% of the global population suffers from these conditions. This represents around 300 million people, i.e. 4% of the world’s population.
When taken together, “rare” diseases are not so rare after all, and therefore public health policies at global and national level are needed to address this issue, according to the authors. Such a policy is becoming reality in France, which launched its 3rd National Rare Diseases Plan a year ago. “In all likelihood, our data represent a low estimation of the reality. The majority of rare diseases are not traceable in healthcare systems and in many countries there are no national registries. Making patients visible within their respective healthcare systems by implementing means to record their precise diagnoses would make it possible in the future not only to review our estimations, but more fundamentally to improve the adaptation of support and reimbursement policies”, specifies Rath.
Other observations were made during this study, with the researchers showing for example that out of the more than 6,000 diseases described in Orphanet, 72% are genetic and 70% start in childhood. Furthermore, among the diseases analyzed in the study, 149 alone are responsible for 80% of cases of rare diseases identified worldwide.
Future research must now focus on collecting and analyzing the data on the rare diseases which had been excluded from this study. Cancers and other rare diseases caused by infectious agents or linked to environmental factors will be the subject of new analyses. But the researchers’ priority remains the same: namely, to broaden the field of knowledge on rare diseases in order to offer patients better treatment and ensure that, in the future, no-one is left behind.
Stéphanie Nguengang Wakap, Deborah M Lambert, Annie Olry, Charlotte
Rodwell, Charlotte Gueydan, Valérie Lanneau, Daniel Murphy, Yann Le Cam, Ana
Estimating cumulative point prevalence of rare diseases: analysis of the Orphanet database.
European Journal of Human Genetics (2019).
Pharmaceutical wholesale products provide savings to clients and customers. Whether you’re in pharmaceutical retail, pharmaceutical supply or home health care, providing the best quality products and services at reasonable prices is the goal.
Health care is expensive for consumers and pharmaceutical suppliers. A trusted pharmaceutical wholesaler keeps costs low, inventory high and gives better buying power to clients. Pharmaceutical wholesalers also provide products for the pharmaceutical retailer. With everything from pain relievers to motor oil available in pharmacies, it’s important to get the best product prices for your retail pharmacy. Wholesale vitamins are big sellers. Pharmacies compete with big box stores, vitamin shops and health food stores for consumer dollars. Getting customers to think of the pharmacy first when purchasing vitamins is a challenge.
Home health care providers rely on wholesale pharmacy supplies for medical equipment, wound care and sterile fields. Wholesale surgical gloves, sterile syringes, bandages and other supplies save patients money.
Pharmaceutical wholesale suppliers will:
- Provide savings on pharmaceutical supplies for pharmaceutical retailers.
- Allow you to pass savings along to clients and patients for high quality care.
- Offer a full line of pharmaceutical products and supplies to retailers, hospitals and home health care companies.
- Help you attract customers with competitive pricing on vitamins and other products.
Purchase wholesale pharmacy supplies for retail pharmacy shops
Whether for an independent pharmacy or a part of a pharmacy chain, wholesale pharmacy supplies just make sense as a way to increase revenue and save money.
Purchase medical wholesale supplies to save customers money
Medical supply costs add up quickly for chronically ill patients. Regular purchasers of diabetic testing supplies, insulin syringes, arthritis treatments, joint support devices and incontinence supplies need every opportunity to save money.
Contract with full service pharmaceutical wholesalers for all your pharmacy needs
Full service pharmaceutical distributors supply their clients with a variety of products and services to meet the needs of clients and customers. A pharmaceuticals provider offering everything from wholesale drugs to over the counter pain relievers saves independent pharmacists and home care companies valuable time as well as money.
Find a pharmaceutical wholesaler that also deals in wholesale vitamins
Vitamins, herbals and supplements are big business in the medical community. Patients using nutritional supplements find relief of symptoms and an improved sense of well being from these products. Making vitamins and supplements available to your customers at competitive prices makes you their one stop source for all health related purchases.
- Visit pharmaceutical wholesaler trade shows to develop relationships with industry specialists.
- Take time to meet with drug reps from various companies that offer significant savings on generic drugs for your customers. Drug reps also offer lots of free samples as an added incentive.